In vitro isolation and identification of human immunodeficiency virus (HIV) variants with reduced sensitivity to C-2 symmetrical inhibitors of HIV type 1 protease.

Protease inhibitors are another class of compounds for treatment of human immunodeficiency virus (HIV)-caused disease. The emergence of resistance to the current anti-HIV drugs makes the determination of potential resistance to protease inhibitors imperative. Here we describe the isolation of an HIV...

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Autores principales: Otto, M J, Garber, S, Winslow, D L, Reid, C D, Aldrich, P, Jadhav, P K, Patterson, C E, Hodge, C N, Cheng, Y S
Formato: Artigo
Lenguaje:Inglês
Publicado: 1993
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC47178/
https://ncbi.nlm.nih.gov/pubmed/8356053
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