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In vitro isolation and identification of human immunodeficiency virus (HIV) variants with reduced sensitivity to C-2 symmetrical inhibitors of HIV type 1 protease.

Protease inhibitors are another class of compounds for treatment of human immunodeficiency virus (HIV)-caused disease. The emergence of resistance to the current anti-HIV drugs makes the determination of potential resistance to protease inhibitors imperative. Here we describe the isolation of an HIV...

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书目详细资料
发表在:	Proc Natl Acad Sci U S A
Principais autores:	Otto, M J, Garber, S, Winslow, D L, Reid, C D, Aldrich, P, Jadhav, P K, Patterson, C E, Hodge, C N, Cheng, Y S
格式:	Artigo
语言:	Inglês
出版:	National Academy of Sciences 1993
主题:	Research Article
在线阅读:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47178/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8356053/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.16.7543
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In vitro isolation and identification of human immunodeficiency virus (HIV) variants with reduced sensitivity to C-2 symmetrical inhibitors of HIV type 1 protease.

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