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The Immp2l mutation causes age‐dependent degeneration of cerebellar granule neurons prevented by antioxidant treatment
Reactive oxygen species are implicated in age‐associated neurodegeneration, although direct in vivo evidence is lacking. We recently showed that mice with a mutation in the Inner Mitochondrial Membrane Peptidase 2‐like (Immp2l) gene had elevated levels of mitochondrial superoxide, impaired fertility...
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| Publicado no: | Aging Cell |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4717271/ https://ncbi.nlm.nih.gov/pubmed/26616244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12426 |
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