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Oxidative stress is involved in age-dependent spermatogenic damage of Immp2l mutant mice

Mitochondrial reactive oxygen species (ROS) have been implicated in spermatogenic damage, although direct in vivo evidence is lacking. We recently generated a mouse in which the Inner Mitochondrial Membrane Peptidase 2-like (Immp2l) gene is mutated. This Immp2l mutation impairs the processing of sig...

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Detalhes bibliográficos
Main Authors: George, Sunil K., Jiao, Yan, Bishop, Colin E., Lu, Baisong
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377857/
https://ncbi.nlm.nih.gov/pubmed/22569411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.04.003
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