Controlling the cytokine storm in severe bacterial diarrhoea with an oral Toll‐like receptor 4 antagonist

Shigella dysenteriae causes the most severe of all infectious diarrhoeas and colitis. We infected rhesus macaques orally and also treated them orally with a small and non‐absorbable polypropyletherimine dendrimer glucosamine that is a Toll‐like receptor‐4 (TLR4) antagonist. Antibiotics were not give...

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Publicado en:Immunology
Main Authors: Islam, Dilara, Lombardini, Eric, Ruamsap, Nattaya, Imerbsin, Rawiwan, Khantapura, Patchariya, Teo, Ian, Neesanant, Pimmnapar, Gonwong, Siriphan, Yongvanitchit, Kosol, Swierczewski, Brett E., Mason, Carl J., Shaunak, Sunil
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2015
Assuntos:
Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717244/
https://ncbi.nlm.nih.gov/pubmed/26496144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12549
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