Evaluation of an intragastric challenge model for Shigella dysenteriae 1 in rhesus monkeys (Macaca mulatta) for the pre-clinical assessment of Shigella vaccine formulations

Shigellosis is a worldwide disease, characterized by abdominal pain, fever, vomiting, and the passage of blood- and mucus-streaked stools. Rhesus monkeys and other primates are the only animals that are naturally susceptible to shigellosis. A suitable animal model is required for the pre-clinical ev...

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Detalhes bibliográficos
Main Authors: Islam, Dilara, Ruamsap, Nattaya, Khantapura, Patchariya, Aksomboon, Ajchara, Srijan, Apichai, Wongstitwilairoong, Boonchai, Bodhidatta, Ladaporn, Gettayacamin, Montip, Venkatesan, Malabi M, Mason, Carl J
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954967/
https://ncbi.nlm.nih.gov/pubmed/24028276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apm.12168
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