CD74/DQA1 dimers predispose to the development of arthritis in humanized mice

Rheumatoid arthritis (RA) is associated with the presence of certain HLA class II genes. However, why some individuals carrying RA non‐associated alleles develop arthritis is still unexplained. The trans‐heterodimer between two RA non‐associated HLA genes can render susceptibility to develop arthrit...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: David, Luckey, Gokhale, Ameya, Jois, Seetharama, Johnson, Aaron, Behrens, Marshall, Luthra, Harvinder, Taneja, Veena
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717240/
https://ncbi.nlm.nih.gov/pubmed/26524976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12551
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