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Trans-heterodimer between two arthritis non-associated HLA alleles can predispose to arthritis

OBJECTIVE: Certain class II alleles are associated with susceptibility to develop arthritis. However, some individuals carrying non-RA associated alleles develop arthritis is still unexplained. An individual heterozygous for both the DQA1 and DQB1 genes, can express the DQ molecule in cis or trans h...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Behrens, Marshall, Papadopoulos, George K., Moustakas, Antonis, Smart, Michele, Luthra, Harvinder, David, Chella S, Taneja, Veena
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3106136/
https://ncbi.nlm.nih.gov/pubmed/21305521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.30260
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