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Transfection of mEpo gene to intestinal epithelium in vivo mediated by oral delivery of chitosan-DNA nanoparticles

AIM: To prepare the chitosan-pmEpo nanoparticles and to study their ability for transcellular and paracellular transport across intestinal epithelia by oral administration. METHODS: ICR mice were fed with recombinant plasmid AAV-tetO-CMV-mEpo (containing mEpo gene) or pCMVβ (containing LacZ gene), w...

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Detalles Bibliográficos
Publicado en:World J Gastroenterol
Main Authors: Chen, Jing, Yang, Wu-Li, Li, Ge, Qian, Ji, Xue, Jing-Lun, Fu, Shou-Kuan, Lu, Da-Ru
Formato: Artigo
Idioma:Inglês
Publicado: Baishideng Publishing Group Inc 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717060/
https://ncbi.nlm.nih.gov/pubmed/14695780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i1.112
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