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Triplet structure of von Willebrand factor reflects proteolytic degradation of high molecular weight multimers.

High molecular weight (HMW) and low molecular weight (LMW) forms of von Willebrand factor (vWF) were isolated from normal human plasma in the presence of protease inhibitors. HMW and LMW vWF preparations were subjected to reduction of interdimeric disulfide bridges under mild reducing conditions. Fo...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Furlan, M, Robles, R, Affolter, D, Meyer, D, Baillod, P, Lämmle, B
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1993
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47170/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8356046/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.16.7503
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