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Silencing of Foxp3 delays the growth of murine melanomas and modifies the tumor immunosuppressive environment

Forkhead box p3 (Foxp3) expression was believed to be specific for T-regulatory cells but has recently been described in non-hematopoietic cells from different tissue origins and in tumor cells from both epithelial and non-epithelial tissues. The aim of this study was to elucidate the role of Foxp3...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Franco-Molina, Moisés A, Miranda-Hernández, Diana F, Mendoza-Gamboa, Edgar, Zapata-Benavides, Pablo, Coronado-Cerda, Erika E, Sierra-Rivera, Crystel A, Saavedra-Alonso, Santiago, Taméz-Guerra, Reyes S, Rodríguez-Padilla, Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716752/
https://ncbi.nlm.nih.gov/pubmed/26834483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S90476
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