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Clinical pharmacology study of cariprazine (MP-214) in patients with schizophrenia (12-week treatment)

PURPOSE: Cariprazine is a potent dopamine D(3)-preferring D(3)/D(2) receptor partial agonist in development for the treatment of schizophrenia, bipolar mania, and depression. Pharmacokinetics of cariprazine and the two clinically relevant metabolites (desmethyl- and didesmethyl-cariprazine) was eval...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Nakamura, Tadakatsu, Kubota, Tomoko, Iwakaji, Atsushi, Imada, Masayoshi, Kapás, Margit, Morio, Yasunori
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716719/
https://ncbi.nlm.nih.gov/pubmed/26834462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S95100
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