Relationship Between Plasma Concentrations and Clinical Effects of Cariprazine in Patients With Schizophrenia or Bipolar Mania

Population pharmacokinetic/pharmacodynamic modeling (via NONMEM) was used to describe longitudinal exposure‐response relationships for total cariprazine (sum of cariprazine and its major active metabolites) in 2,558 patients with schizophrenia or bipolar mania. Drug exposure metrics were explored fo...

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書目詳細資料
發表在:Clin Transl Sci
Main Authors: Periclou, Antonia, Willavize, Susan, Jaworowicz, David, Passarell, Julie, Carrothers, Timothy, Ghahramani, Parviz, Durgam, Suresh, Earley, Willie, Kapás, Margit, Khariton, Tatiana
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2019
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7070889/
https://ncbi.nlm.nih.gov/pubmed/31664765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12720
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