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Genotype Imputation with Millions of Reference Samples

We present a genotype imputation method that scales to millions of reference samples. The imputation method, based on the Li and Stephens model and implemented in Beagle v.4.1, is parallelized and memory efficient, making it well suited to multi-core computer processors. It achieves fast, accurate,...

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Bibliografiska uppgifter
I publikationen:Am J Hum Genet
Huvudupphovsmän: Browning, Brian L., Browning, Sharon R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Elsevier 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716681/
https://ncbi.nlm.nih.gov/pubmed/26748515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2015.11.020
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