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Genotype Imputation with Millions of Reference Samples
We present a genotype imputation method that scales to millions of reference samples. The imputation method, based on the Li and Stephens model and implemented in Beagle v.4.1, is parallelized and memory efficient, making it well suited to multi-core computer processors. It achieves fast, accurate,...
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| Udgivet i: | Am J Hum Genet |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4716681/ https://ncbi.nlm.nih.gov/pubmed/26748515 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2015.11.020 |
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