Phospho-mTOR is not upregulated in metastatic SDHB paragangliomas

BACKGROUND: Pheochromocytomas (PCCs)/paragangliomas (PGLs) are neuroendocrine tumours that may cause arrhythmia and death if untreated. Treatment for patients with metastatic tumours is lacking. As new PCC/PGL susceptibility genes are discovered that are associated with the mTOR pathway, treatment t...

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Veröffentlicht in:Eur J Clin Invest
Hauptverfasser: Ghayee, Hans K., Giubellino, Alessio, Click, Arielle, Kapur, Payal, Christie, Alana, Xie, Xian-Jin, Martucci, Victoria, Shay, Jerry W., Souza, Rhonda F., Pacak, Karel
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716658/
https://ncbi.nlm.nih.gov/pubmed/23889685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/eci.12127
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