Aristolochic acid exposure in Romania and implications for renal cell carcinoma

BACKGROUND: Aristolochic acid (AA) is a nephrotoxicant associated with AA nephropathy (AAN) and upper urothelial tract cancer (UUTC). Whole-genome sequences of 14 Romanian cases of renal cell carcinoma (RCC) recently exhibited mutational signatures consistent with AA exposure, although RCC had not b...

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Detaylı Bibliyografya
Yayımlandı:Br J Cancer
Asıl Yazarlar: Turesky, Robert J, Yun, Byeong Hwa, Brennan, Paul, Mates, Dana, Jinga, Viorel, Harnden, Patricia, Banks, Rosamonde E, Blanche, Helene, Bihoreau, Marie-Therese, Chopard, Priscilia, Letourneau, Louis, Lathrop, G Mark, Scelo, Ghislaine
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Short Communication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716534/
https://ncbi.nlm.nih.gov/pubmed/26657656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.402
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