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Loss of Drosophila i-AAA protease, dYME1L, causes abnormal mitochondria and apoptotic degeneration
Mitochondrial AAA (ATPases Associated with diverse cellular Activities) proteases i-AAA (intermembrane space-AAA) and m-AAA (matrix-AAA) are closely related and have major roles in inner membrane protein homeostasis. Mutations of m-AAA proteases are associated with neuromuscular disorders in humans....
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| Veröffentlicht in: | Cell Death Differ |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4716308/ https://ncbi.nlm.nih.gov/pubmed/26160069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.94 |
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