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Necroptosis is preceded by nuclear translocation of the signaling proteins that induce it

A signaling pathway that induces programmed necrotic cell death (necroptosis) was reported to be activated in cells by several cytokines and various pathogen components. The major proteins participating in that pathway are the protein kinases RIPK1 and RIPK3 and the pseudokinase mixed lineage kinase...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Yoon, S, Bogdanov, K, Kovalenko, A, Wallach, D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716306/
https://ncbi.nlm.nih.gov/pubmed/26184911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.92
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