Nuclear ULK1 promotes cell death in response to oxidative stress through PARP1

Reactive oxygen species (ROS) may cause cellular damage and oxidative stress-induced cell death. Autophagy, an evolutionarily conserved intracellular catabolic process, is executed by autophagy (ATG) proteins, including the autophagy initiation kinase Unc-51-like kinase (ULK1)/ATG1. Although autopha...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Joshi, A, Iyengar, R, Joo, J H, Li-Harms, X J, Wright, C, Marino, R, Winborn, B J, Phillips, A, Temirov, J, Sciarretta, S, Kriwacki, R, Peng, J, Shelat, A, Kundu, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716304/
https://ncbi.nlm.nih.gov/pubmed/26138443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.88
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