A pump-pore model for transmembrane transport of hydrophilic solutes.
Transmembrane transport of a hydrophilic solute is presumed to begin when hydrated ligand adheres in Velcro-like fashion to hydrated membrane surface. Asymmetric physical forces cause rolling movements of ligand over membrane surface until contact occurs with appropriate transport machinery, consist...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1993
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47160/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8102798/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.16.7456 |
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