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A pump-pore model for transmembrane transport of hydrophilic solutes.

Transmembrane transport of a hydrophilic solute is presumed to begin when hydrated ligand adheres in Velcro-like fashion to hydrated membrane surface. Asymmetric physical forces cause rolling movements of ligand over membrane surface until contact occurs with appropriate transport machinery, consist...

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Pubblicato in:Proc Natl Acad Sci U S A
Autore principale: Roberts, E
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1993
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47160/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8102798/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.16.7456
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