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Disrupting protein tyrosine phosphatase σ does not prevent sympathetic axonal dieback following myocardial infarction

The neuronal receptor protein tyrosine phosphatase receptor σ (PTPσ) inhibits axonal extension upon binding to chondroitin sulfate proteoglycans (CSPGs) in scar tissue. We recently demonstrated that modulating or deleting PTPσ promoted re-innervation of the CSPG-containing cardiac scar after ischemi...

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Pubblicato in:Exp Neurol
Autori principali: Johnsen, Dustin, Olivas, Antoinette, Lang, Bradley, Silver, Jerry, Habecker, Beth
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715993/
https://ncbi.nlm.nih.gov/pubmed/26616238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2015.11.011
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