Noncoding RNA NORAD regulates genomic stability by sequestering PUMILIO proteins

Long noncoding RNAs (lncRNAs) have emerged as regulators of diverse biological processes. Here we describe the initial functional analysis of a poorly characterized human lncRNA (LINC00657) that is induced after DNA damage, which we termed Noncoding RNA Activated by DNA Damage or NORAD. NORAD is hig...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Lee, Sungyul, Kopp, Florian, Chang, Tsung-Cheng, Sataluri, Anupama, Chen, Beibei, Sivakumar, Sushama, Yu, Hongtao, Xie, Yang, Mendell, Joshua T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715682/
https://ncbi.nlm.nih.gov/pubmed/26724866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.12.017
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