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Autophagy in the CNS and periphery coordinate lipophagy and lipolysis in the brown adipose tissue and liver
Autophagy degrades lipid droplets (LD) via lipophagy. Cytosolic lipases, ATGL and HSL, are canonical mechanisms for lipolysis. Whether autophagy proteins engage in direct crosstalk with lipases to promote lipid mobilization remains unknown. The integrative physiology of an inter-organ communication...
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| Udgivet i: | Cell Metab |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4715637/ https://ncbi.nlm.nih.gov/pubmed/26698918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.10.008 |
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