Autophagy in the CNS and periphery coordinate lipophagy and lipolysis in the brown adipose tissue and liver

Autophagy degrades lipid droplets (LD) via lipophagy. Cytosolic lipases, ATGL and HSL, are canonical mechanisms for lipolysis. Whether autophagy proteins engage in direct crosstalk with lipases to promote lipid mobilization remains unknown. The integrative physiology of an inter-organ communication...

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Publicado en:Cell Metab
Autores principales: Martinez-Lopez, Nuria, Garcia-Macia, Marina, Sahu, Srabani, Athonvarangkul, Diana, Liebling, Emily, Merlo, Paola, Cecconi, Francesco, Schwartz, Gary J., Singh, Rajat
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715637/
https://ncbi.nlm.nih.gov/pubmed/26698918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.10.008
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