Autophagy in the CNS and periphery coordinate lipophagy and lipolysis in the brown adipose tissue and liver

Autophagy degrades lipid droplets (LD) via lipophagy. Cytosolic lipases, ATGL and HSL, are canonical mechanisms for lipolysis. Whether autophagy proteins engage in direct crosstalk with lipases to promote lipid mobilization remains unknown. The integrative physiology of an inter-organ communication...

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Dades bibliogràfiques
Publicat a:Cell Metab
Autors principals: Martinez-Lopez, Nuria, Garcia-Macia, Marina, Sahu, Srabani, Athonvarangkul, Diana, Liebling, Emily, Merlo, Paola, Cecconi, Francesco, Schwartz, Gary J., Singh, Rajat
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715637/
https://ncbi.nlm.nih.gov/pubmed/26698918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2015.10.008
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