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Synthesis and Use of a Phosphonate-amidine to Generate an Anti-phosphoarginine Specific Antibody

Protein arginine phosphorylation is a post-translational modification (PTM) that is important for bacterial growth and virulence. Despite its biological relevance, the intrinsic acid lability of phosphoarginine (pArg) have impaired studies of this novel PTM. Herein, we report for the first time the...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Fuhrmann, Jakob, Subramanian, Venkataraman, Thompson, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715515/
https://ncbi.nlm.nih.gov/pubmed/26458230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201506737
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