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Oral VP-16-213 in advanced bronchogenic carcinoma and toxic effects when combined with methotrexate.

Forty-six patients with histologically confirmed lung cancer received treatment with the cytotoxic drug VP-16-213 in a dose of 100 mg twice daily, given orally for five days. The overall objective response rate was 11 out of 46 (24%) or 11 of the 33 (33%) who survived to receive two cycles. The drug...

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Detalhes bibliográficos
Main Authors: Anderson, G, Bowyer, F, Williams, L
Formato: Artigo
Idioma:Inglês
Publicado em: 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC471534/
https://ncbi.nlm.nih.gov/pubmed/7314017
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