Transforming Growth Factor-β–Independent Role of Connective Tissue Growth Factor in the Development of Liver Fibrosis

We previously identified transforming growth factor (TGF)-β signaling as a fibronectin-independent mechanism of type I collagen fibrillogenesis following adult liver injury. To address the contribution of TGF-β signaling during the development of liver fibrosis, we generated adult mice lacking TGF-β...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Sakai, Keiko, Jawaid, Safdar, Sasaki, Takako, Bou-Gharios, George, Sakai, Takao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715221/
https://ncbi.nlm.nih.gov/pubmed/25108224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.06.009
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