Tropomyosin diffusion over actin subunits facilitates thin filament assembly

Coiled-coil tropomyosin binds to consecutive actin-subunits along actin-containing thin filaments. Tropomyosin molecules then polymerize head-to-tail to form cables that wrap helically around the filaments. Little is known about the assembly process that leads to continuous, gap-free tropomyosin cab...

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Bibliographic Details
Published in:Struct Dyn
Main Authors: Fischer, Stefan, Rynkiewicz, Michael J., Moore, Jeffrey R., Lehman, William
Format: Artigo
Language:Inglês
Published: American Crystallographic Association 2016
Subjects:
SPECIAL TOPIC: PROTEIN DYNAMICS
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714992/
https://ncbi.nlm.nih.gov/pubmed/26798831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4940223
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