Distinct mechanisms define murine B cell lineage immunoglobulin heavy chain (IgH) repertoires

Processes that define immunoglobulin repertoires are commonly presumed to be the same for all murine B cells. However, studies here that couple high-dimensional FACS sorting with large-scale quantitative IgH deep-sequencing demonstrate that B-1a IgH repertoire differs dramatically from the follicula...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Yang, Yang, Wang, Chunlin, Yang, Qunying, Kantor, Aaron B, Chu, Hiutung, Ghosn, Eliver EB, Qin, Guang, Mazmanian, Sarkis K, Han, Jian, Herzenberg, Leonore A
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2015
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714975/
https://ncbi.nlm.nih.gov/pubmed/26422511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09083
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