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Liver-to-plasma vaniprevir (MK-7009) concentration ratios in HCV-infected patients
BACKGROUND: Some drugs that are actively taken up into the liver exhibit greater than dose proportional increases in plasma exposure, although human liver-to-plasma concentration ratios have rarely been evaluated. Understanding these relationships has implications for drug concentrations at the targ...
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| Publicado no: | Antivir Ther |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4714953/ https://ncbi.nlm.nih.gov/pubmed/25849338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP2958 |
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