Liver-to-plasma vaniprevir (MK-7009) concentration ratios in HCV-infected patients

BACKGROUND: Some drugs that are actively taken up into the liver exhibit greater than dose proportional increases in plasma exposure, although human liver-to-plasma concentration ratios have rarely been evaluated. Understanding these relationships has implications for drug concentrations at the targ...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antivir Ther
Egile Nagusiak: Wright, D Hamish, Caro, Luzelena, Cerra, Michael, Panorchan, Paul, Du, Lihong, Anderson, Melanie, Potthoff, Andrej, Nachbar, Robert B, Wagner, John, Manns, Michael P, Talal, Andrew H
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714953/
https://ncbi.nlm.nih.gov/pubmed/25849338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3851/IMP2958
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