Early Regulation of Profibrotic Genes in Primary Human Cardiac Myocytes by Trypanosoma cruzi

The molecular mechanisms of Trypanosoma cruzi induced cardiac fibrosis remains to be elucidated. Primary human cardiomyoctes (PHCM) exposed to invasive T. cruzi trypomastigotes were used for transcriptome profiling and downstream bioinformatic analysis to determine fibrotic-associated genes regulate...

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Publicado en:PLoS Negl Trop Dis
Autores principales: Udoko, Aniekanabassi N., Johnson, Candice A., Dykan, Andrey, Rachakonda, Girish, Villalta, Fernando, Mandape, Sammed N., Lima, Maria F., Pratap, Siddharth, Nde, Pius N.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714843/
https://ncbi.nlm.nih.gov/pubmed/26771187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003747
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