Early Regulation of Profibrotic Genes in Primary Human Cardiac Myocytes by Trypanosoma cruzi

The molecular mechanisms of Trypanosoma cruzi induced cardiac fibrosis remains to be elucidated. Primary human cardiomyoctes (PHCM) exposed to invasive T. cruzi trypomastigotes were used for transcriptome profiling and downstream bioinformatic analysis to determine fibrotic-associated genes regulate...

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Dades bibliogràfiques
Publicat a:PLoS Negl Trop Dis
Autors principals: Udoko, Aniekanabassi N., Johnson, Candice A., Dykan, Andrey, Rachakonda, Girish, Villalta, Fernando, Mandape, Sammed N., Lima, Maria F., Pratap, Siddharth, Nde, Pius N.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714843/
https://ncbi.nlm.nih.gov/pubmed/26771187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003747
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