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T cell-independent and T cell-dependent immunoglobulin G responses to polyomavirus infection are impaired in complement receptor 2-deficient mice

Polyomavirus (PyV) infection induces protective T cell-independent (TI) IgM and IgG antibody responses in T cell-deficient mice, but these responses are not generated by immunization with viral proteins or virus like particles. We hypothesized that innate signals contribute to the generation of isot...

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Publicado en:Virology
Main Authors: Szomolanyi-Tsuda, Eva, Seedhom, Mina O., Carroll, Michael C., Garcea, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714765/
https://ncbi.nlm.nih.gov/pubmed/16733062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2006.04.018
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