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Spotlight on ixazomib: potential in the treatment of multiple myeloma

Despite the significant therapeutic advances achieved with proteasome inhibitors (PIs) such as bortezomib and carfilzomib in prolonging the survival of patients with multiple myeloma, the development of drug resistance, peripheral neuropathy, and pharmacokinetic limitations continue to pose major ch...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Muz, Barbara, Ghazarian, Rachel Nicole, Ou, Monica, Luderer, Micah John, Kusdono, Hubert Daniel, Azab, Abdel Kareem
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714737/
https://ncbi.nlm.nih.gov/pubmed/26811670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S93602
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