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The Use of Covariates and Random Effects in Evaluating Predictive Biomarkers Under a Potential Outcome Framework

Predictive or treatment selection biomarkers are usually evaluated in a subgroup or regression analysis with focus on the treatment-by-marker interaction. Under a potential outcome framework (Huang, Gilbert and Janes [Biometrics 68 (2012) 687–696]), a predictive biomarker is considered a predictor f...

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Bibliografiske detaljer
Udgivet i:Ann Appl Stat
Main Authors: Zhang, Zhiwei, Nie, Lei, Soon, Guoxing, Liu, Aiyi
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714717/
https://ncbi.nlm.nih.gov/pubmed/26779295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1214/14-AOAS773
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