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SF3B1 and EIF1AX mutations occur in primary leptomeningeal melanocytic neoplasms; yet another similarity to uveal melanomas

INTRODUCTION: Like uveal melanomas, primary leptomeningeal melanocytic neoplasms (LMNs) frequently carry GNAQ and GNA11 mutations. However, it is currently unknown whether these LMNs harbor mutations in BAP1, SF3B1 and/or EIF1AX like uveal melanomas as well. In this study, we used Sanger sequencing...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Küsters-Vandevelde, Heidi V. N., Creytens, David, Grunsven, Adriana C. H. van Engen-van, Jeunink, Marcel, Winnepenninckx, Veronique, Groenen, Patricia J. T. A., Küsters, Benno, Wesseling, Pieter, Blokx, Willeke A. M., Prinsen, Clemens F. M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714515/
https://ncbi.nlm.nih.gov/pubmed/26769193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0272-0
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