Complex regulation of ADAR-mediated RNA-editing across tissues

BACKGROUND: RNA-editing is a tightly regulated, and essential cellular process for a properly functioning brain. Dysfunction of A-to-I RNA editing can have catastrophic effects, particularly in the central nervous system. Thus, understanding how the process of RNA-editing is regulated has important...

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Pubblicato in:BMC Genomics
Autori principali: Huntley, Melanie A., Lou, Melanie, Goldstein, Leonard D., Lawrence, Michael, Dijkgraaf, Gerrit J.P., Kaminker, Joshua S., Gentleman, Robert
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714477/
https://ncbi.nlm.nih.gov/pubmed/26768488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-2291-9
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