Identification and spontaneous immune targeting of an endogenous retrovirus K envelope protein in the Indian rhesus macaque model of human disease

BACKGROUND: Endogenous retroviruses (ERVs) are remnants of ancient retroviral infections that have invaded the germ line of both humans and non-human primates. Most ERVs are functionally crippled by deletions, mutations, and hypermethylation, leading to the view that they are inert genomic fossils....

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Detalhes bibliográficos
Publicado no:Retrovirology
Main Authors: Wu, Helen L., Léon, Enrique J., Wallace, Lyle T., Nimiyongskul, Francesca A., Buechler, Matthew B., Newman, Laura P., Castrovinci, Philip A., Paul Johnson, R., Gifford, Robert J., Brad Jones, R., Sacha, Jonah B.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Short Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714462/
https://ncbi.nlm.nih.gov/pubmed/26767784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-016-0238-0
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