Focused Analysis of Exome Sequencing Data for Rare Germline Mutations in Familial and Sporadic Lung Cancer

BACKGROUND: The association between smoking induced chronic obstructive pulmonary disease (COPD) and lung cancer (LC) is well documented. Recent genome-wide association studies (GWAS) have identified 28 susceptibility loci for LC, 10 for COPD, 32 for smoking behavior (SM), and 63 for pulmonary funct...

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Detalhes bibliográficos
Publicado no:J Thorac Oncol
Main Authors: Liu, Yanhong, Kheradmand, Farrah, Davis, Caleb F, Scheurer, Michael E., Wheeler, David, Tsavachidis, Spiridon, Armstrong, Georgina, Simpson, Claire, Mandal, Diptasri, Kupert, Elena, Anderson, Marshall, You, Ming, Xiong, Donghai, Pikielny, Claudio, Schwartz, Ann G., Bailey-Wilson, Joan, Gaba, Colette, De Andrade, Mariza, Yang, Ping, Pinney, Susan M., Amos, Christopher I., Spitz, Margaret R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714038/
https://ncbi.nlm.nih.gov/pubmed/26762739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2015.09.015
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