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Direct effect of chronic hypoxia in suppressing large conductance Ca(2+)‐activated K(+) channel activity in ovine uterine arteries via increasing oxidative stress
Chronic hypoxia has a direct effect in down‐regulating the BK(Ca) channel β1 subunit and inhibiting the BK(Ca) channel activity in uterine arteries of pregnant sheep. Oxidative stress plays a causal role in hypoxia‐mediated suppression of BK(Ca) channel function. The steroid hormone‐induced effect o...
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| Publié dans: | J Physiol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4713733/ https://ncbi.nlm.nih.gov/pubmed/26613808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP271626 |
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