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Neuroinflammation impairs adaptive structural plasticity of dendritic spines in a preclinical model of Alzheimer’s disease

To successfully treat Alzheimer’s disease (AD), pathophysiological events in preclinical stages need to be identified. Preclinical AD refers to the stages that exhibit amyloid deposition in the brain but have normal cognitive function, which are replicated in young adult APPswe/PS1deltaE9 (deltaE9)...

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Podrobná bibliografie
Vydáno v:Acta Neuropathol
Hlavní autoři: Zou, Chengyu, Shi, Yuan, Ohli, Jasmin, Schüller, Ulrich, Dorostkar, Mario M., Herms, Jochen
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713725/
https://ncbi.nlm.nih.gov/pubmed/26724934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1527-8
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