Neuroinflammation impairs adaptive structural plasticity of dendritic spines in a preclinical model of Alzheimer’s disease

To successfully treat Alzheimer’s disease (AD), pathophysiological events in preclinical stages need to be identified. Preclinical AD refers to the stages that exhibit amyloid deposition in the brain but have normal cognitive function, which are replicated in young adult APPswe/PS1deltaE9 (deltaE9)...

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Bibliografiske detaljer
Udgivet i:Acta Neuropathol
Main Authors: Zou, Chengyu, Shi, Yuan, Ohli, Jasmin, Schüller, Ulrich, Dorostkar, Mario M., Herms, Jochen
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2016
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Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713725/
https://ncbi.nlm.nih.gov/pubmed/26724934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-015-1527-8
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