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The aggregation of cytochrome C may be linked to its flexibility during refolding
Large-scale expression of biopharmaceutical proteins in cellular hosts results in production of large insoluble mass aggregates. In order to generate functional product, these aggregates require further processing through refolding with denaturant, a process in itself that can result in aggregation....
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| Publicado no: | 3 Biotech |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4713397/ https://ncbi.nlm.nih.gov/pubmed/28330101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13205-015-0345-y |
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