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The Protonation State of the Cross-linked Tyrosine during the Catalytic Cycle of Cytochrome c Oxidase

Cytochrome c oxidase is the terminal complex of the respiratory chain in mitochondria and some aerobic bacteria and is responsible for most of the O(2) consumption in biology. The key reaction in the catalysis of O(2) reduction is O–O bond scission that requires four electrons and a proton. In our r...

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Autori principali: Gorbikova, Elena A., Wikström, Mårten, Verkhovsky, Michael I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259884/
https://ncbi.nlm.nih.gov/pubmed/18931371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803511200
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