HUMAN GRK4γ(142V) VARIANT PROMOTES AT(1)R-MEDIATED HYPERTENSION VIA RENAL HDAC1 INHIBITION

The influence of a single gene on the etiology of essential hypertension may be difficult to ascertain, unless the gene interacts with other genes that are germane to blood pressure regulation. G protein-coupled receptor kinase type 4 (GRK4) is one such gene. We have reported that the expression of...

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Veröffentlicht in:Hypertension
Hauptverfasser: Wang, Zheng, Zeng, Chunyu, Villar, Van Anthony M., Chen, Shi-You, Konkalmatt, Prasad, Wang, Xiaoyan, Asico, Laureano D., Jones, John E., Yang, Yu, Sanada, Hironobu, Felder, Robin A., Eisner, Gilbert M., Weir, Matthew R., Armando, Ines, Jose, Pedro A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713262/
https://ncbi.nlm.nih.gov/pubmed/26667412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.115.05962
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