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Epigenetic control of Apolipoprotein E expression mediates gender-specific hematopoietic regulation

Epigenetic alterations play a central role in the control of normal and malignant blood cell development. We demonstrate here that expression of a truncated DNA methyltransferase 3B isoform DNMT3B7, which has been shown to alter cellular epigenetic patterns, decreases the overall number of hematopoi...

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Pubblicato in:Stem Cells
Autori principali: Vasanthakumar, Aparna, Zullow, Hayley, Lepore, Janet B., Thomas, Kenya, Young, Natalie, Anastasi, John, Reardon, Catherine A., Godley, Lucy A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713251/
https://ncbi.nlm.nih.gov/pubmed/26417967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2214
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