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Sequential posttranslational modifications regulate PKC degradation
Cross-talk among different types of posttranslational modifications (PTMs) has emerged as an important regulatory mechanism for protein function. Here we elucidate a mechanism that controls PKCα stability via a sequential cascade of PTMs. We demonstrate that PKCα dephosphorylation decreases its sumo...
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| 發表在: | Mol Biol Cell |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The American Society for Cell Biology
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4713141/ https://ncbi.nlm.nih.gov/pubmed/26564794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-09-0624 |
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