Mitochondrial E3 ubiquitin ligase MARCH5 controls mitochondrial fission and cell sensitivity to stress-induced apoptosis through regulation of MiD49 protein

Ubiquitin- and proteasome-dependent outer mitochondrial membrane (OMM)-associated degradation (OMMAD) is critical for mitochondrial and cellular homeostasis. However, the scope and molecular mechanisms of the OMMAD pathways are still not well understood. We report that the OMM-associated E3 ubiquiti...

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Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Xu, Shan, Cherok, Edward, Das, Shweta, Li, Sunan, Roelofs, Brian A., Ge, Shealinna X., Polster, Brian M., Boyman, Liron, Lederer, W. Jonathan, Wang, Chunxin, Karbowski, Mariusz
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713136/
https://ncbi.nlm.nih.gov/pubmed/26564796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-09-0678
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