Arl13b and the exocyst interact synergistically in ciliogenesis

Arl13b belongs to the ADP-ribosylation factor family within the Ras superfamily of regulatory GTPases. Mutations in Arl13b cause Joubert syndrome, which is characterized by congenital cerebellar ataxia, hypotonia, oculomotor apraxia, and mental retardation. Arl13b is highly enriched in cilia and is...

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Pubblicato in:Mol Biol Cell
Autori principali: Seixas, Cecília, Choi, Soo Young, Polgar, Noemi, Umberger, Nicole L., East, Michael P., Zuo, Xiaofeng, Moreiras, Hugo, Ghossoub, Rania, Benmerah, Alexandre, Kahn, Richard A., Fogelgren, Ben, Caspary, Tamara, Lipschutz, Joshua H., Barral, Duarte C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2016
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713133/
https://ncbi.nlm.nih.gov/pubmed/26582389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E15-02-0061
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