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The Role of Rac1 in the Growth Cone Dynamics and Force Generation of DRG Neurons

We used optical tweezers, video imaging, immunocytochemistry and a variety of inhibitors to analyze the role of Rac1 in the motility and force generation of lamellipodia and filopodia from developing growth cones of isolated Dorsal Root Ganglia neurons. When the activity of Rac1 was inhibited by the...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Sayyad, Wasim A., Fabris, Paolo, Torre, Vincent
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713067/
https://ncbi.nlm.nih.gov/pubmed/26766136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146842
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