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The Role of Rac1 in the Growth Cone Dynamics and Force Generation of DRG Neurons

We used optical tweezers, video imaging, immunocytochemistry and a variety of inhibitors to analyze the role of Rac1 in the motility and force generation of lamellipodia and filopodia from developing growth cones of isolated Dorsal Root Ganglia neurons. When the activity of Rac1 was inhibited by the...

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Библиографические подробности
Опубликовано в: :PLoS One
Главные авторы: Sayyad, Wasim A., Fabris, Paolo, Torre, Vincent
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4713067/
https://ncbi.nlm.nih.gov/pubmed/26766136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146842
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